Biological cell parameter change test method and apparatus

Details Biological cell parameter change test method and apparatus Biological cell parameter change test method and apparatus

1980-02-05

1981-07-14

Tokar, Michael J.

Electricity: measuring and testing

Determining nonelectric properties by measuring electric...

Erosion

235 92PC, G01N 2700

Patent

active

042789362

ABSTRACT:
By subjecting cells, such as blood cells, tissue cells, and bone marrow cells, to hypotonic solutions having different osmolalities, the cells will rapidly attain a change in volume and electrical resistance parameters, which change is measurable, for example, by a Coulter Counter.RTM. particle measuring instrument. The relationship between change in cell resistance or cell volume and osmolality provides a discriminator between normality, different diseases, and certain inherited differences.

REFERENCES:
patent: 2656508 (1953-10-01), Coulter
patent: 3259842 (1968-07-01), Coulter et al.
patent: 3982183 (1976-09-01), Collineau et al.
patent: 4041385 (1977-08-01), Gulliford et al.

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