Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1974-09-23
1979-09-11
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
424245, 424287, 424289, 424294, 424295, 424319, A61K 3700, A61K 31555, A61K 3128, A61K 31315
Patent
active
041675649
ABSTRACT:
A method for improving the stability of amino acid-metal complexes or chelates and enhancing the uptake of these complexes into biological tissues. This method comprises forming the metal complexes with amino acids or hydrolyzed proteins and incorporating into them a buffer system which controls the pH of the complex and its surrounding media. This uptake is accomplished by the system of amino acid active transport into the blood stream from which the complex is then carried throughout the entire body.
REFERENCES:
patent: 2982690 (1961-05-01), Ratcliff
patent: 3168541 (1965-02-01), Hobbs
patent: 3367834 (1968-02-01), Dexter
patent: 3463858 (1969-08-01), Anderson
patent: 3466312 (1969-09-01), Ercoli
Miller Pharmacal Co., International Surgery Official Journal of the International College of Surgeons, Nov. 1971.
Chaberek and Martell, Organic Sequestering Agents, John Wiley & Sons, Inc., New York (1959), pp. 198-199; 203; 494-495.
Kirk-Othmer, Encyclopedia of Chemical Technology, vol. 6, pp. 14-18; 21-24 (1965).
Albion Laboratories, Inc.
Waddell Frederick E.
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