Biological agent-containing ceramic coating and method

Details Biological agent-containing ceramic coating and method Biological agent-containing ceramic coating and method

2006-08-08

2006-08-08

Robert, Eduardo C. (Department: 3733)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Bone

Reexamination Certificate

active

07087086

ABSTRACT:
The invention provides an implantable article, a method of preparing the same, and methods of modifying a ceramic-coated implantable article. The implantable article comprises a biocompatible substrate and a bioactive ceramic surface coating into which a biological agent is incorporated. The preparation and modification of an implantable article involve incubating a biocompatible substrate surface or pre-existing ceramic coating thereon with a composition comprising (i) a biological agent, (ii) calcium ions, (iii) phosphate ions, and (iv) a liquid carrier.

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