Biologic electrode array with integrated optical detector

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C204S412000, C204S413000, C422S068100, C422S082010, C422S082020, C422S082030, C422S082050, C436S073000, C436S079000, C436S086000, C436S089000, C436S093000, C436S094000, C436S095000, C436S106000, C436S107000, C436S108000, C436S111000, C436S127000, C436S128000, C436S131000, C436S164000, C436S172000, C436S501000, C436S518000

Reexamination Certificate

active

07045097

ABSTRACT:
A biologic electrode array is formed on a semiconductor substrate. A matrix of electrode sites is disposed on the semiconductor substrate. A matrix of optical detectors is disposed beneath the electrode sites in the semiconductor substrate, wherein each electrode site is associated with a corresponding optical detector. The optical detectors are coupled to detection circuitry formed on the semiconductor substrate. The electrode sites may include slitted electrodes, punctuated electrodes, or optically transparent electrodes.

REFERENCES:
patent: 3430072 (1969-02-01), Stevens
patent: 3957592 (1976-05-01), Young
patent: 4280815 (1981-07-01), Oberhardt et al.
patent: 4772851 (1988-09-01), Schattschneider
patent: 4787963 (1988-11-01), MacConnell
patent: 4924224 (1990-05-01), Takahashi et al.
patent: 5039490 (1991-08-01), Marsoner et al.
patent: 5093268 (1992-03-01), Leventis et al.
patent: 5178161 (1993-01-01), Kovacs
patent: 5314495 (1994-05-01), Kovacs
patent: 5341215 (1994-08-01), Seher
patent: 5378343 (1995-01-01), Kounaves et al.
patent: 5434049 (1995-07-01), Okano et al.
patent: 5445934 (1995-08-01), Fodor et al.
patent: 5500188 (1996-03-01), Hafeman et al.
patent: 5527670 (1996-06-01), Stanley
patent: 5605662 (1997-02-01), Heller et al.
patent: 5632876 (1997-05-01), Zanzucchi et al.
patent: 5632957 (1997-05-01), Heller et al.
patent: 5653939 (1997-08-01), Hollis et al.
patent: 5849486 (1998-12-01), Heller et al.
patent: 5965452 (1999-10-01), Kovacs
patent: 6017696 (2000-01-01), Heller et al.
patent: 6048690 (2000-04-01), Heller et al.
patent: 6051380 (2000-04-01), Sosnowski et al.
patent: 6054270 (2000-04-01), Southern
patent: 6066448 (2000-05-01), Wohlstadter et al.
patent: 6258606 (2001-07-01), Kovacs
patent: 6682936 (2004-01-01), Kovacs
patent: 0 376 611 (1990-07-01), None
patent: 594170 (1994-04-01), None
patent: WO 93/22678 (1993-11-01), None
patent: WO 95/12808 (1995-05-01), None
Eggers, M. et al, BioTechniques 1994, 17, 516-520, 522, 524-525.
R.J. Reay, et al., “Microfabricated Electrochemical Analysis System for Heavy Metal Detection,” Sensors and Actuators B 34 (1996), pp. 450-455.
H. Meyer, et al., “Two-Dimensional Imaging of O2, H2O2, and Glucose Distributions by an Array of 400 Individually Addressable Microelectrodes,” Anal. Chem. (1995), 67, p. 1164-1170.
G. Fuhr, et al., “Travelling Wave-Driven Microfabricated Electrohydrodynamic Pumps for Liquids,” J. Micromech. Microeng. 4 (1994), pp. 217-226.
T. Livache, et al., “Preparation of a DNA Matrix Via an Electrochemically Directed Copolymerization of Pyrrole and Oligonucleotides Bearing a Pyrrole Group,” Nucleic Acids Research (1994), vol. 22, No. 15, pp. 2915-2921.
G.C. Fiaccabrino, et al., “Array of Individually Addressable Microelectrodes,” Sensors and Actuators B, 18-19 (1994), pp. 675-677.
T. Hermes, et al., “An Amperometric Microsensor Array With 1024 Individually Addressable Elements For Two-Dimensional Concentration Mapping,” Sensors and Actuators B 21 (1994) pp. 33-37.
R. Kakerow, et al., “A Monolithic Sensor Array of Individually Addressable Microelectrodes,” Sensors and Actuators A, 43 (1994) pp. 296-301.
P.R. Fielden, et al., “Voltammetric Information From Arrays of Individually Controlled Electrodes: Their Potential for Industrial Process Measurements,” Analytica Chimica Acta, 273 (1993) pp. 111-121.
G.T. Hermanson, et al., “Immobilized Affinity Ligand Techniques,” Academic Press, Inc. (1992) pp. 410-417.
P. Connolly, et al., “Microelectronic and Nanoelectronic Interfacing Techniques for Biological Systems,” Sensors and Actuators B 6 (1992) pp. 113-121.
T.K. Whitehurst, et al., “Actively-Scanned Microelectrode Arrays,” 22ndAnnual Meeting of the Society for Neuroscience (1992) vol. 18, Abstract 22.24.
J.C. Hoogvliet, et al., “Multichannel Amperometric Detection System for Liquid Chromatography and Flow Injection Analysis,” Anal. Chem. 63 (1991), pp. 2418-2423.
R.F. Taylor, “Immobilized Antibody- and Receptor-Based Biosensors,” (1991) pp. 262-303.
D.E. Tallman, et al., “A Wide Bandwidth Computer Based Potentiostat for Fast Voltammetry at Microelectrodes,” J. Electroanal. Chem. 280 (1990), pp. 327-340.
M.S. Harrington, et al., “Multiple Electrode Potentiostat,” Rev. Sci. Instrum. 60 (10), (Oct. 1989), pp. 3323-3328.
P.C. Meunier, et al., “High-Accuracy Oxygen Polarograph for Photosynthetic Systems,” Rev. Sci. Instrum. 59 (3), (Mar. 1988), pp. 486-491.
G. Yuhang, et al., “Microcomputer Controlled FFT Electrochemical Impedance Measurement System,” Journal of Wuhan University, Natural Science Edition (Wuhan daxue xuebao (ziran kexus bao), No. 3, 1987, pp. 65-71.
D.W. Dees, et al., “Experimental Observations of Free-Convection Mass Transfer to a Horizontal Surface With a Micromosaic Electrode,” J. Electrochem. Soc., vol. 134, No. 2, (Feb. 1987), pp. 369-377.
Y. Gu, et al., Wuhan Daxue Xuebao, Ziran Kexueban, 1987, 65-71.
J.G. Pentari, et al., “Construction and Applications of a Microcomputer Controlled Pulsed Amperometric Detector System,” Anal. Instrum., 15 (4) (1986),pp. 329-345.
P.R. Gray, et al., “MOS Operational Amplifier Design—A Tutorial Overview,” IEEE Journal of Solid-State Circuits, vol. SC-17, No. 6, (Dec. 1982), pp. 969-982.
J.J. Zipper, et al., “Computer-Controlled Monitoring and Data Reduction for Multiple Ion-Selective Electrodes in a Flowing System,” Anal. Chem. vol. 46, (1974), pp. 2111-2118.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Biologic electrode array with integrated optical detector does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biologic electrode array with integrated optical detector, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biologic electrode array with integrated optical detector will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3602818

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.