Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical energy applicator
Reexamination Certificate
1998-05-05
2001-05-29
Jastrzaf, Jeffrey R. (Department: 3762)
Surgery: light, thermal, and electrical application
Light, thermal, and electrical application
Electrical energy applicator
C607S002000, C128S898000, C424S569000
Reexamination Certificate
active
06238429
ABSTRACT:
This invention is related to cardiac interventional systems and devices and may provide numerous therapies and device applications which are heretofore unknown. with the development of biologic cabling many new devices and therapies become possible where conduction of a physiologically active signal to one part of the body is needed.
BACKGROUND
Much interest has been generated in the scientific, engineering and medical communities regarding the adaptation of living cells to perform additional functions. There has been some work of Dr. Loren Field of Indianapolis in which cardiomyocetes have been modified to repair or replace heart tissue. While it has been demonstrated that small patches of cardiac or other muscular tissue can be grown and suggested that such patches can be placed within or on particular organs, including the heart, the development of a specific and novel form of cellular structure, not found in nature, has not been described to the knowledge of this inventor. This structure which we will call “Biologic Cabling” is not an organism but a building block for alternative tissue pathways for electrical signal conduction throughout a living body.
Already, there are banks of stem cells and other cells are now available which can be used to develop particular tissues for various uses, but no one has provided a structure well suited to conducting electrical activity throughout a living body comprised primarily or exclusively of living cells.
It should be noted that by using the most biologically friendly materials, living cells themselves, many of the present problems with implantable device/body interface issues are negated. For example, in the pacemaker area, it is not advisable to attach anything to the left ventricular internal wall or put it in that chamber because of the propensity of such additions to throw clots which can easily then be lodged in the brain.
It will become apparent to the reader that there are numerous applications for biologic cabling.
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Long-Term Survival of AT-1 Cardiomyocyte Grafts in Syngeneic Mycardium (Rapid Communication pp H1727-H 1733) Gou Young Koh et al.
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Donovan Maura G.
Markowitz H. Toby
Mehdi Khawar
Atlass Michael B.
Jastrzaf Jeffrey R.
Medtronic Inc.
Patton Harold R.
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