Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...
Patent
1998-09-23
1999-12-21
Yaskos, John D.
Surgery
Means for introducing or removing material from body for...
Treating material introduced into or removed from body...
604141, A61M 1100
Patent
active
060042877
ABSTRACT:
A biolistic apparatus is provided with a housing having a carrier membrane disposed in a chamber for movement relative to an outlet plate having a plurality of apertures therein. The carrier membrane has a plurality of micro-particles adhered thereto on the surface of the membrane adjacent the apertures for delivery into cells or tissue. A plurality of rupturable membranes are mounted in spaced relation to the carrier membrane. Initially, a vacuum is provided within the assembly including the outlet opening to purge the apparatus of any undesirable gasses. High pressure helium is then delivered to the rupturable membranes and upon reaching a predetermined pressure, will cause the membranes to rupture allowing a shock front of high pressure helium to strike the carrier membrane and impel the articles through the outlet openings.
REFERENCES:
patent: 5569190 (1996-10-01), D'Antonio
patent: 5599302 (1997-02-01), Lilley et al.
patent: 5851198 (1998-12-01), Castellano et al.
patent: 5919159 (1999-07-01), Lilley et al.
Celeste Joe
Loomis Dale J
Sanford John
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