Bioerodible thermoset elastomers

Details Bioerodible thermoset elastomers Bioerodible thermoset elastomers

1991-06-17

1993-06-08

Lipman, Bernard

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Aftertreated polymer

424 7801, 424 7808, A61K 3174

Patent

active

052177122

ABSTRACT:
Bioerodible, thermoset, covalently crosslinked, elastomeric poly(ortho ester)s are disclosed. These materials are comprised of polymer chains that are interlocked in a covalent, three dimensional network which imparts dimensional stability. Use of these thermoset, covalently crosslinked materials as a drug delivery device is also disclosed.

REFERENCES:
patent: 4304767 (1981-12-01), Heller et al.
patent: 4549010 (1985-10-01), Sparer et al.
patent: 4735804 (1988-04-01), Caldwell et al.
patent: 4758436 (1988-07-01), Caldwell et al.
"In Vitro and In Vivo Release of Levongestrel from Poly(ortho esters)", Heller et al., Journal of Controlled Release, 1(1985) 233-238.

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