Bioerodible polymers for solid controlled release pharmaceutical

Details Bioerodible polymers for solid controlled release pharmaceutical Bioerodible polymers for solid controlled release pharmaceutical

1993-11-15

1995-10-24

Seidleck, James J.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

From organic oxygen-containing reactant

424486, 424423, 424457, 514179, 568831, C08G 6534

Patent

active

054611407

ABSTRACT:
Bioerodible ortho ester polymers useful for preparing solid form bioerodible pharmaceutical compositions such as pellets, capsules, suppositories and the like are provided. A novel synthetic method for preparing the polymers is provided as well as is a novel triol reactant. Synthesis involves a one-step reaction between a monomeric ortho ester and a triol. The pharmaceutical compositions of the invention are useful for the controlled release of therapeutic agents, and may be administered for a variety of purposes.

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