Bioerodible polymeric semi-interpenetrating network alloys for s

Details Bioerodible polymeric semi-interpenetrating network alloys for s Bioerodible polymeric semi-interpenetrating network alloys for s

1997-04-18

2000-06-06

Merriam, Andrew E. C.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Processes of preparing a desired or intentional composition...

523114, 523115, 524414, 525411, 525415, 525439, 525445, 525903, 623 16, 424426, A61F 200, C08K 324

Patent

active

060719826

ABSTRACT:
A bioerodible polymeric semi-IPN alloy which comprises a first bioerodible polymer capable of producing acidic products upon hydrolytic degradation; a second bioerodible polymer, which provides a biopolymeric scaffolding or internal reinforcement; and optionally a buffering compound that buffers the acidic products within a desired pH range. In a preferred embodiment, the second bioerodible polymer comprises polypropylene fumarate (PPF), which is cross-linked, desirably by a vinyl monomer such as vinyl pyrrolidone (VP) to form the biopolymeric scaffolding which provides the semi-IPN with dimensional and geometric stability.

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