Bioerodible implants

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Monomer contains oxygen

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424422, 424423, 424426, 424486, 514953, A61K 914, A61F 202

Patent

active

058372288

ABSTRACT:
A bioerodible controlled release dosage form is disclosed comprising a polymer formed by condensing beneficial agents having a hydroxyl functionality of two or more with diketene acetals or divinyl ethers which delivers beneficial agents to a biological environment of use. A statistically significant portion of the beneficial agent is covalently bonded within the polymer matrix.

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Chemical Abstracts, 111, No. 16, Abstract #140344a (1989).
Chow, A.W., Hamlin, R.D., Heller, J., "Cure Behavior of Neat and and Drug-Loaded Poly(ortho ester) Bioerodible Implants", Journal of Controlled Release, 9, 123-131 (1989).

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