Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1997-09-15
1999-04-06
Azpuru, Carlos
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424434, 5147723, 5147726, 514944, A61F 1302, A61K 4730, A61K 4732
Patent
active
058914587
ABSTRACT:
The invention relates to a muco-adherent, soluble device for administering active ingredients, a method of using said device, and an improved method of manufacturing said device using a continuous, enclosed mixing device capable of operating under pressure. The devices of the invention, which comprise a lyophilized foam and an active ingredient, have a dissolution time of at least about 8 hours, and preferably at least about 24 hours, and can provide for the sustained and/or controlled release of an active ingredient for up to about 24 hours.
REFERENCES:
patent: 4494580 (1985-01-01), Browning
Britton Peter
Flanagan Patricia
Hart William P.
Linkin Deborah
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