Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1988-04-21
1993-10-05
Dentz, Bernard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 18, 530330, A61K 3700
Patent
active
052505162
ABSTRACT:
An elastomeric material, capable of reversibly contracting and relaxing by an inverse temperature transition, in a form suitable for use as a protective layer between a mammalian repair site and a second tissue site whereby adhesion involving said repair site and said second tissue site is substantially prevented.
REFERENCES:
patent: 4605413 (1986-08-01), Urry et al.
D. W. Urry et al., "A New Class of Elastomeric Biomaterials: Dynamic .beta.-Spirals Comprised of Sequential Polypeptides," Polym. Prepr. (Am. Chem. Soc. Div. Polym. Chem.) (1983) 24(1):3-4.
D. W. Urry et al., "Temperature-correlated Force and Structure Development in Elastomeric Polypeptides: The Ile Analog of the Polypentapeptide of Elastin," Biopolymers (1986) 25:1939-1953.
D. W. Urry et al., "Compounding of Elastin Polypentapeptide to Collagen Analog: A Potential Elastomeric Prosthetic Material," Biomat. Med. Dev. Art. Org. (1981) 9(3):181-194.
D. W. Urry et al., "Prolyl Hydroxylation of the Polypentapeptide Model of Elastin Impairs Fiber Formation," Biochem. and Biophys. Res. Comm. (1979) 90(1):194-198.
Dentz Bernard
UAB Research Foundation
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