Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Bone
Patent
1984-05-14
1986-06-24
Griffin, Ronald W.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Implantable prosthesis
Bone
623 22, 424 14, 424 95, A61F 228, A61F 232, C07G 700
Patent
active
045965749
ABSTRACT:
Disclosed is a biodegradable porous ceramic delivery system useful for delivery of bone morphogenic protein (BMP) to viable tissue and to induce formation of new bone therein. The delivery composite is substantially pure BMP in combination with a biodegradable porous ceramic (sintered), e.g. beta-tricalcium phosphate, and may be prepared by admixing the BMP with the porous ceramic material. The composition is implanted in viable tissue where the BMP is slowly released and induces formation of new bone.
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Hench, L. L. et al., J. Biomedical Mater. Res. Symposium No. 4, pp. 25-42, "Direct Chemical Bond of Bioactive Glass-Ceramic Materials to Bone and Muscle," (1973).
Griffin Ronald W.
The Regents of the University of California
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