Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only
Patent
1981-12-28
1983-04-05
Nielsen, Earl A.
Drug, bio-affecting and body treating compositions
Solid synthetic organic polymer as designated organic active...
Polymer from ethylenic monomers only
128 1R, 128 92B, 128 92C, 528354, C08G 6308
Patent
active
043791387
ABSTRACT:
Homopolymers and copolymers of lactones are prepared by ring-opening polymerization of a mixture of lactones which includes a monolactone, such as .epsilon.-caprolactone, and a dilactone, such as bis-2,2-(.epsilon.-caprolacton-4-yl)propane, which is capable of forming crosslinks. The resulting polymers range from tough and partially crystalline to amorphous, elastomeric materials, depending on the monomer composition and proportions. Additionally, these polymers may be designed to achieve different degrees of permeability and rates of biodegradation. As such, they are useful for the controlled delivery of medicinal agents and as surgical aids and temporary artificial biomaterials such as skin substitutes and burn dressings.
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Pitt Colin G.
Schindler Anton E.
Nielsen Earl A.
Research Triangle Institute
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