Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1997-10-15
1999-08-03
Krass, Frederick
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 53, 514 57, 525 541, 525 5411, 525 542, 525 543, 527200, 527207, 527300, 527311, 527315, C08G 6348, C08G 6391, C08L 8900
Patent
active
059325399
ABSTRACT:
Novel biodegradable amphiphilic polymers are described. Preferred polymers have a lipophilic binding moiety coupled covalently to a hydrophilic tissue adhesion moiety through a divalent linker comprising a natural metabolite or a polymer biodegradable into a natural metabolite. In one embodiment the biodegradable polymers of the invention exhibit the property of self-assembly characteristic of liquid crystals. The present amphiphilic biodegradable polymers can be used alone or in combination with other biocompatible polymers, with cells, growth factors, hormones, and/or other pharmaceutical agents in fabrication of implantable matrices for tissue repair. The polymers are biodegradable into art-recognized biocompatible components, preferably natural metabolites.
REFERENCES:
patent: 4347234 (1982-08-01), Wahlig et al.
patent: 4438198 (1984-03-01), Schmer
patent: 5085861 (1992-02-01), Gerhart et al.
patent: 5197973 (1993-03-01), Pang et al.
patent: 5464929 (1995-11-01), Bezwada et al.
patent: 5668288 (1997-09-01), Storey et al.
S. Miyamoto and K. Takaoka, "Bone Induction And Bone Repair By Composites Of Bone Morphogenetic Protein And Biodegradable Synthetic Polymers", Annales Chirurgiae et Gynaecologiae 82:69-76, 1993.
Shimpei Miyamoto, et al., "Polylactic Acid-Polyethylene Glycol Block Copolymer", Clinical Orthopaedics and Related Research, No. 294, Sep. 1993, pp. 333-343.
J.O. Hollinger and G.C. Battistone, "Biodegradable Bone Repair Materials", Clinical Orthopaedics and Related Research, No. 207, Jun. 1986, pp. 290-305.
Iyer Subramani
Stupp Samuel I.
Krass Frederick
The Board of Trustees of the University of Illinois
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