Biodegradable polyacetal polymers and methods for their formatio

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – From aldehyde or derivative thereof as reactant

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528230, 528232, 528239, 525400, 525401, 525403, 525405, 525417, 514693, 514696, 424 7808, C08G 400

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active

058115102

ABSTRACT:
The present invention relates to biodegradable biocompatible polyacetals, methods for their preparation, and methods for treating mammals by administration of biodegradable biocompatible polyacetals. A method for forming the biodegradable biocompatible polyacetals combines a glycol-specific oxidizing agent with a polysaccharide to form an aldehyde intermediate which is combined with a reducing agent to form the biodegradable biocompatible polyacetal. The resultant biodegradable biocompatible polyacetals can be chemically modified to incorporate additional hydrophilic moieties. A method for treating mammals includes the administration of the biodegradable biocompatible polyacetal in which biologically active compounds or diagnostic labels can be disposed.

REFERENCES:
patent: 4024073 (1977-05-01), Shimizu et al.
patent: 5202434 (1993-04-01), Wilkening
patent: 5359071 (1994-10-01), Durette et al.
patent: 5460752 (1995-10-01), Fredj t al.

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