Biodegradable ocular insert for controlled delivery of ophthalmi

Details Biodegradable ocular insert for controlled delivery of ophthalmi Biodegradable ocular insert for controlled delivery of ophthalmi

1981-07-09

1984-03-27

Apley, Richard J.

Surgery

Controlled release therapeutic device or system

Osmotic or diffusion pumped device or system

604893, A61M 700

Patent

active

044391986

ABSTRACT:
An ocular insert is disclosed that is attachable to the third eyelid of animals to provide controlled delivery of ophthalmic medication. The insert includes a disc impregnated with medication in controlled-release form and a biodegradable spear for attachment of the insert to the third eyelid. An insert effective for treatment of infectious bovine keratoconjunctivitis comprises a disc impregnated with chloramphenicol sodium monosuccinate and a spear of biodegradable polylactic acid which provides for retention of the insert in the eye, and consequent medication, for up to seven days.

REFERENCES:
patent: 3598115 (1971-08-01), Horne
patent: 4186184 (1980-01-01), Zaffaroni
patent: 4201210 (1980-05-01), Hughes et al.

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