Biodegradable nonionic contrast media

Details Biodegradable nonionic contrast media Biodegradable nonionic contrast media

1998-11-04

2000-06-06

Powers, Fiona T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbonate esters

560132, 564153, 564158, 424 945, 424 9453, 424 9454, 424 9455, C07C27148, C07C 6996, A01N 4904

Patent

active

060720697

ABSTRACT:
Novel non-ionic contrast media are provided, which fulfill the requirements for x-ray visualization media, while being biodegradable. The compounds are characterized by being triiodo-3,5-diaminobenzoic acid derivatives, where the functional groups are derivatized with hydroxyalkyl groups and the amino functionalities are further derivatized with acyl substituents of one carbon acids. Also, triiodophloroglucinol oxyalkyl substituted derivatives are provided.

REFERENCES:
patent: 4278654 (1981-07-01), Rakli
Kalsch et al. (1999) Science of the Total Environment 225: 143-153.
Kummerer et al. (1998) Chemosphere 36: 11: 2437-2445.
Rode et al. (Aug. 1998) Applied & Environmental Microbiology 64:8:3114-3117.
Steger-Hartmann, et al. (1999) Ecotoxicology and Environmental Safety 42:274-281.

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