Stock material or miscellaneous articles – Web or sheet containing structurally defined element or... – Including a second component containing structurally defined...
Patent
1992-12-22
1995-01-17
Resan, Stevan A.
Stock material or miscellaneous articles
Web or sheet containing structurally defined element or...
Including a second component containing structurally defined...
428332, 42840224, 428407, 428900, 436173, B32B 2702
Patent
active
053824687
ABSTRACT:
Subdomain metal or metal oxide particles covalently coupled to chemically reactive organic moieties and subsequently reacted together to form biodegradable magnetic microclusters are disclosed. The magnetic microcluster can be used as contrast agents in NMR imaging for the production of images suitable for use in diagnosis, for in vivo delivery and targeting of drugs, as in vivo, biodegradable agents for the sequestering of free metal ions in the treatment of metal driven disease.
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patent: 5147573 (1992-09-01), Chagnon
patent: 5213788 (1993-05-01), Ranney
J. Appl. Phys. vol. 41, No. 3, Mar. 1970, pp. 1064-1072 R. Kaiser et al "Magnetic Properties of Stable Dispersions of Subdomain Magnetite Particles".
Invest Radiol. vol. 27, No. 6, Jun. 1992, pp. 450-455 A. Iannone "Detection and Quantification in Rat Tissues of Magnetite as Demonstrated by Electron Spin Resonance Spectroscopy".
Carter Michelle J.
Chagnon Mark S.
Ferris John R.
Fiore Barry L.
Hamilton Tracy J.
Molecular Bioquest, Inc.
Resan Stevan A.
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