Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices
Patent
1990-02-01
1991-08-20
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Matrices
424423, 424426, 424488, 424499, 424450, 514937, A61K 914, A61K 950, A61K 3722, A61E 200
Patent
active
050412922
ABSTRACT:
A biodegradable hydrogel matrix is provided, useful for the controlled release of pharmacologically active agents. The matrix is formed by cross-linking a proteinaceous component and a polysaccharide or mucopolysaccharide, and then loading a selected drug therein. By varying temperature, ionic strength, and the composition of the hydrogel matrix, one can control degradation kinetics, the degree of uptake of a particular pharmacologically active agent, and the overall times release profile.
REFERENCES:
patent: 3663687 (1972-05-01), Evans
patent: 4357259 (1982-11-01), Senyei et al.
patent: 4526714 (1985-07-01), Feijen et al.
patent: 4670014 (1987-06-01), Huc et al.
patent: 4837381 (1989-06-01), Steber et al.
patent: 4849210 (1989-07-01), Widden
patent: 4853226 (1989-08-01), Machida et al.
patent: 4871716 (1989-10-01), Longo et al.
patent: 4895724 (1990-01-01), Cardinal et al.
Chemically Cross-Linked Albumin Microsphere-Davis et al., J. of Controlled Release, 4, 293-302 (1987).
Kishore G. S.
Page Thurman K.
TheraTech Inc.
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