Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Patent
1992-10-29
1995-11-14
Saunders, David
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
427 211, 427127, 427212, 42721331, 42721333, 427214, 427216, 427337, 427402, 427414, 427 213, 427 214, 428403, 436524, 436525, 436526, 436528, 436529, 436532, 436534, 5303911, 530810, 530812, 530813, G01N 33531, G01N 33543, G01N 33548
Patent
active
054666090
ABSTRACT:
The invention relates generally to colloidal particle having a core material and a gelatin/aminodextran coating with pendent functional groups attached thereto. Biological substances or molecules, especially monoclonal antibodies, may be attached to said particles. The monoclonal antibody containing particles are useful in a variety of positive and negative biological assays.
REFERENCES:
patent: 3970518 (1976-07-01), Giaever
patent: 4010038 (1977-03-01), Iwasaki et al.
patent: 4210418 (1980-07-01), Brown et al.
patent: 4253844 (1981-03-01), Limet et al.
patent: 4264766 (1981-04-01), Fischer
patent: 4267234 (1981-05-01), Rembaum
patent: 4358388 (1982-11-01), Daniel et al.
patent: 4452773 (1984-06-01), Molday
patent: 4454234 (1984-06-01), Czerlinski
patent: 4478946 (1984-10-01), Van der Merwe et al.
patent: 4554088 (1985-11-01), Whitehead et al.
patent: 4582622 (1986-04-01), Ikeda et al.
patent: 4783336 (1988-11-01), Margel et al.
patent: 4795698 (1989-01-01), Owen et al.
patent: 4920061 (1990-04-01), Poynton et al.
patent: 4965007 (1990-10-01), Yudelson
patent: 5062991 (1991-11-01), Siiman et al.
patent: 5164311 (1992-11-01), Gupta
K. Nustad et al., "Monodisperse Polymer Particles in Immunoassays and Cell Separation", Microspheres, Medical and Biological Applications, A. Rembaum and Z. A. Tukes, Eds. (Boca Raton: CRC Press, 1988) Chapter 4 pp. 53-75.
C. D. Platsoucas et al., "The Use of Magnetic Monosized Polymer Particles for the Removal of T cells from Human Bone Marrow Suspension", Microspheres: Med. and Biol. Appl., Op. cit., Chapter 6, pp. 89-98.
J. Lyklema, Colloids and Surfaces, 10: 33-42 (1984), "Proteins at Solid-Liquid Interfaces".
N. Kawanishi et al., J. Phys. Chem. 94: 4611-4617 (1990), "Measurement of the Interaction between Adsorbed Polyelectrolytes: Gelatin on Mica Surfaces."
Meltzer et al., J. Colloid and Interface Sci. 126: 292-302 (1988), "Adsorption of Collagen . . . to Glass and to Each Other."
A. Oseroff, et al., Proc. Natl. Acad. Sci. USA 83: 8744-8748.
J. March, Advanced Organic Chemistry: Reactions, Mechanisms and Structure (McGraw-Hill, New York 1968) pp. 666-669, 682-685 and 866-869.
L. B. Shih et al., Int. J. Cancer 41: 832-839 (1988).
R. S. Molday FEBS 170: 232-238 (1984).
R. Mrsny et al., Eur. J. Cell Biology 45: 200-208 (1987); "A novel approach . . . affinity-gold labeling of Na, K-ATPase."
D. Hicks et al., Invest. Opthalmology & Visual Sci. 26: 1002-1013 (1985), "Localization . . . Using Dextran-Gold Markers."
H. O. House, Modern Synthetic Reactions, 2nd Ed. (W. A. Benjamin, Inc. Menlo Park, Calif. 1972) pp. 853-859.
Burshteyn Alexander
Gupta Ravinder K.
Siiman Olavi
Chin Christopher L.
Coulter Corporation
Kaye Michelle A.
Saunders David
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