Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1992-09-28
1994-01-25
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424422, 424423, 424425, 623 16, A61K 3532
Patent
active
052814190
ABSTRACT:
An antibiotic impregnated fracture fixation device and antibiotic impregnated drug delivery polymer are provided. In a preferred embodiment, a homogenous mixture of thermally melted poly(lactic) acid and at least one antibiotic and/or antibacterial agent are employed.
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Garvin et al., "Treatment of Canine Osteomyelitis with a Biodegradable Antibiotic Implant," 38th Annual Meeting ORS, Wash. D.C., Feb. 17-20, 1992.
Lin et al., "Evaluation of a biodegradable drug delivery system for chronic osteomyelitis," 38th Annual Meeting, ORS, Wash. D.C., Feb. 17-20, 1992.
Robinson et al., "Preparation and degradation of a biodegradable gentamycin delivery system for the treatment of osteomyelitis," 38th Annual Meeting, ORS, Wash. D.C., Feb. 17-20, 1992.
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Weston et al., 37th Annual Meeting, ORS, Anaheim, Calif., Mar. 4-7, 1991.
Lin Sheldon S.
Tuan Rocky S.
Kulkosky Peter F.
Page Thurman K.
Thomas Jefferson University
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