Biodegradable copolymer, and polymeric micelle composition...

Details Biodegradable copolymer, and polymeric micelle composition... Biodegradable copolymer, and polymeric micelle composition...

2003-12-29

2010-02-02

Hartley, Michael G. (Department: 1618)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

Reexamination Certificate

active

07655258

ABSTRACT:
A biodegradable copolymer with a core block comprising bioresorbable hydrophobic polyester segment and from 3 to 10 shell blocks comprising hydrophilic polyethylene glycol segment. The hydrophobic polyester segment and each of the hydrophilic polyethylene glycol segments are linked by a urethane linkage. A polymeric micelle composition containing the copolymer is also provided. The copolymer forms micelles when the concentration of the copolymer in a dispersing medium reaches or exceeds the critical micelle concentration. The micelles possess good drug and bioactive agent delivery characteristics and are suitable for use in drug delivery or cosmetic applications.

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