Biodegradable amphipathic copolymers

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...

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523105, 523309, 525 541, 525 542, 525 57, 525309, 525356, 525403, 525404, 525405, 525154, 525410, 525411, 525412, 525413, 525414, 527200, 527300, 524503, 524505, C08L 502, C08L 5300, C08L 7102, C08L 8900

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047451602

ABSTRACT:
A pharmaceutically or veterinarily acceptable amphipathic, non-cross linked linear, branched or graft block copolymer, which has a minimum weight average molecular-weight of 1000, in which the hydrophobic component is biodegradable or hydrolytically unstable under normal physiological conditions, and the hydrophilic component may or may not be biodegradable or hydrolytically unstable under such conditions, and which copolymer is self-dispersible in water; together with mixtures of such a copolymer and a drug, which may be water-soluble of water-insoluble, which mixtures are self-dispersible in water; and processes for the manufacture of such copolymers and such mixtures.

REFERENCES:
patent: 3651008 (1972-03-01), Moser et al.
patent: 3773919 (1973-11-01), Boswell
patent: 3887699 (1975-06-01), Yolles
patent: 4018736 (1977-04-01), Fabian et al.
patent: 4526938 (1986-07-01), Churchill

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