Biodegradable amphipathic copolymers

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only

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424 81, 424486, 523309, A61K 4700

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active

048776068

ABSTRACT:
A pharmaceutically or veterinarily acceptable amphipathic, non-cross linked linear, branched or graft block copolymer, which has a minimum weight average molecular-weight of 1000, in which the hydrophobic component is biodegradable or hydrolytically unstable under normal physiological conditions, and the hydrophilic component may or may not be biodegradable or hydrolytically unstable under such conditions, and which copolymer is self-dispersible in water; together with mixtures of such a copolymer and a drug, which may be water-soluble or water-insoluble, which mixtures are self-dispersible in waterf; and processes for the manufacture of such copolymers and such mixtures.

REFERENCES:
patent: 3651008 (1972-03-01), Moser et al.
patent: 3773919 (1973-11-01), Boswell
patent: 3887699 (1975-06-01), Yolles
patent: 4018736 (1977-04-01), Fabian et al.
patent: 4526938 (1986-07-01), Chruchill
"Dictionary of Science and Technology": Editor T. C. Collocott M. A. W. & R. Chambers (1971).
"Concise Chemical and Technical Dictionary" Edited by H. Bennett, F.A.I.C., Director, B. R. Laboratories (1986).

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