Biocompatible polyurethanes modified with lower alkyl sulfonate

Details Biocompatible polyurethanes modified with lower alkyl sulfonate Biocompatible polyurethanes modified with lower alkyl sulfonate

1987-06-03

1989-11-14

Kight, John

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

528 49, 528 71, C08F28304, C08G 1828, C08G 1870

Patent

active

048808830

ABSTRACT:
Modified-polyurethane block copolymers and devices formed therefrom demonstrate excellent biocompatibility and improved physical and mechanical properties. In a preferred embodiment, from about 5 to about 25 percent of urethane hydrogen atoms are replaced with propyl sulfonate and propyl carboxylate groups to provide the modified copolymer.

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patent: 4689386 (1987-08-01), Chapman et al.
Lelah et al., "Polyether-Urethane Ionomers Surface Property/ ex Vivo Blood Compatability Relationships", J. Coll. Interf. Sci., 104, 422-439 (1985), (Article I).
Lelah et al., "Ex vivo Interactions and Surface Property Relationships of Polyetherurethanes", J. Biomed. Mater. Res., 20, 433-468 (1986), (Article II).
Hwang et al., "Properties of Polyurethane Anionomers: Ionization via Bimolecular Nucleophilic Displacement of Urethane Hydrogen", J. Macromol. Sci. Phys., B23, 153-174 (1984).

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