Biocompatible medical article and method

Details Biocompatible medical article and method Biocompatible medical article and method

1996-11-14

1998-07-21

Weiss, John G.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Arterial prosthesis

Stent structure

623 11, 424422, 424423, 427 224, A61F 202

Patent

active

057829080

ABSTRACT:
A medical article having a metal or glass surface with the surface having an adherent coating of improved biocompatibility. The coating is made by first applying to the surface an silane compound having a pendant vinyl functionality such that the silane adheres to the surface and then, in a separate step, forming a graft polymer on the surface with applied vinylsilane such that the pendant vinyl functionality of the vinylsilane is incorporated into the graft polymer by covalent bonding with the polymer. Biomolecules may then be covalently attached to the base layer.

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