Biocompatible materials

Details Biocompatible materials Biocompatible materials

1996-09-10

1998-01-27

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

514822, 523112, 523113, A61F 202

Patent

active

057119597

ABSTRACT:
A biocompatible material comprising a substrate and a phospholipid moiety covalently attached thereto in an amount and orientation effective to provide an improved nonthrombogenic surface relative to the substrate without the phospholipid moiety covalently attached thereto is provided. In particularly preferred embodiments, the biocompatible material has the following structure: ##STR1## wherein: R.sup.1 is a (C.sub.1 -C.sub.30)alkyl group; R.sup.2 is a (C.sub.1 -C.sub.30)alkylene group; m is 1-4; n is 1-4; and L is a divalent linking group covalently bonded to the substrate and to the phospholipid moiety.

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