Biocompatible intraocular light-screening compositions and metho

Drug – bio-affecting and body treating compositions – Topical sun or radiation screening – or tanning preparations

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Details

351161, 351162, 351163, 351160R, 351160H, 427 2, 514912, 514149, 623 6, A61K 740, A61K 742

Patent

active

050081020

ABSTRACT:
Temporary, light-absorbing, ocularly biocompatible compositions include at least one biocompatible, light-absorbing substance in an amount sufficient to block substantially all light of desired wavelengths and protect susceptible ocular tissues from light induced damage, where the composition is placed introcularly between the light source and ocular tissues susceptible to damage from such light. These compositions can be used to coat or to impregnate intraocular lenses, either before or after insertion of the lenses into the eye, or can be placed intraocularly, in the anterior chamber, over the pupil, in the posterior chamber or in the capsular bag of an eye, as during an ophthalmic procedure. Where the composition includes a viscous, biocompatible, space-maintaining substance such as sodium hyaluronate, chondroitin sulfate, methylcellulose or polyacrylamide, the composition also protects the endothelium, maintains space within the eye, moves tissues, allows focal application of the light-absorbing substance, and permits rapid reversal or pupillary occlusion.

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