Biocompatible crosslinked gel

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

Reexamination Certificate

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Details

C514S772000, C514S781000, C514S782000, C525S054100, C525S054200

Reexamination Certificate

active

08052990

ABSTRACT:
The invention relates to a method for producing a biocompatible crosslinked gel consisting in crosslinking a determined quantity of at least one type of liquid biocompatible polymer by adding a quantity of crosslinking agent, in carrying out a crosslinking reaction, in adding an additional quantity of liquid polymer whose molecular mass is greater than 500,000 Da, in solving the reaction mixture in such a way that the total concentration of the liquid polymer is reduced, in crosslinking and in stopping the crosslinking reaction by removing the crosslinking agent. The inventive gel and the use thereof are also disclosed.

REFERENCES:
patent: 5827937 (1998-10-01), Ågerup
patent: 6060582 (2000-05-01), Hubbell et al.
patent: 6165489 (2000-12-01), Berg et al.
patent: 6174999 (2001-01-01), Miller et al.
patent: 2002/0049281 (2002-04-01), Zhao et al.
patent: 2003/0232198 (2003-12-01), Lamberti et al.
patent: 0 161 887 (1985-11-01), None
patent: 96/33751 (1996-10-01), None
patent: 97/04012 (1997-02-01), None
patent: 02/06350 (2002-01-01), None

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