Biocompatible crosslinked coating and crosslinkable coating...

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Having plural layers

Reissue Patent

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Details

C623S001110, C623S023570, C623S023700, C526S277000, C526S287000, C526S288000, C526S319000

Reissue Patent

active

RE040816

ABSTRACT:
delete-start id="DEL-S-00001" date="20090630" ?A braided stent (1) for transluminal implantation in body lumens is self-expanding and has a radial expanded configuration in which the angle α between filaments is acute. Some or all of filaments (6,7) are welded together in pairs at each end (4,5) of the stent to provide beads (8), thereby strengthening the stent and assisting its deployment from a delivery device. The stent is preferably completely coated using a biocompatible polymeric coating, said polymer preferably having pendant phosphoryl choline groups. A method of making the stent by braiding and welding is described as well as a delivery device for deploying the device.delete-end id="DEL-S-00001" ?insert-start id="INS-S-00001" date="20090630" ?The present invention provides a biocompatible crosslinked coating and a crosslinkable coating polymer composition for forming such a coating. The biocompatible crosslinked coating may be formed by curing a polymer of 23 mole % (methacryloyloxy ethyl)-2-(trimethylammonium ethyl)phosphate inner salt, 47 mole%lauryl methacrylate, 5 mole%γtrimethoxysilyl propyl methacrylate and 25 mole%of hydroxy propyl methacrylate. The crosslinkable coating polymer may include 23 mole% (methacryloyloxy ethyl)-2-(trimethylammonium ethyl)phosphate inner salt, 47 mole%lauryl methacrylate, 5 mole%γtrimethoxysilyl propyl methacrylate and 25 mole%of hydroxy propyl methacrylate.insert-end id="INS-S-00001" ?

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