Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1998-11-19
2000-12-26
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424422, 424424, 424425, 424428, A61F 200, A61F 1300
Patent
active
061654868
ABSTRACT:
Blends of biodegradable polymers, preferably poly(caprolactone) and poly(D,L-lactic-co-glycolic) acid are discussed as well as their applications in the medical field, particularly with regard to bone tissue engineering. Preferably, hydroxyapatite ("HA") granules are incorporated into the blends and the resulting blends have desirable mechanical, physical, and biological characteristics. Even more preferably the compositions of the present invention are utilized to form osteoconductive composites that supported bone cell growth on the surface as well as throughout the scaffold.
REFERENCES:
patent: 4624256 (1986-11-01), Messier et al.
patent: 5475063 (1995-12-01), Kaplan et al.
patent: 5522895 (1996-06-01), Mikos
patent: 5679723 (1997-10-01), Cooper et al.
patent: 5766618 (1998-06-01), Laurencin et al.
Calvert Jay Wynn
Kumta Prashant N.
Marra Kacey G.
Weiss Lee E.
Carnegie Mellon University
Ghali Isis
Miller Raymond A.
Page Thurman K.
University of Pittsburgh
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