Biocompatible coated article

Details Biocompatible coated article Biocompatible coated article

1996-10-10

1998-04-14

Cameron, Erma

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Analysis, diagnosis, measuring, or testing product

427 225, 427 23, 427 231, 427 10, 427498, 427501, 427503, 427551, B05D 306

Patent

active

057389020

ABSTRACT:
The biocompatibility of polymeric and metallic articles used in contact with blood can be substantially improved by coating the articles as described. The coating materials are triblock copolymers of the polylactone-polysiloxane-polylactone type. Optimum biocompatibility is provided by a coating of optimum surface concentration. Porous membranes can be coated as described, providing improved biocompatibility of blood oxygenators, hemodialyzers and the like.

REFERENCES:
patent: 4533566 (1985-08-01), Evans et al.
patent: 4594262 (1986-06-01), Kreil et al.
patent: 4759948 (1988-07-01), Hashimoto et al.
patent: 4814198 (1989-03-01), Baecklund
patent: 5162131 (1992-11-01), Rantanen et al.
Tsai et al, ASAIO Journal, 1994, M619-M624.
Letter dated Oct. 18, 1996 from Fish & Richardson, P.C. to COBE Laboratories, Inc. referring to a metal article coated with Thoratec SMA-300 and BPS-215, with attached price list and invoice.
Gemmell, C.H. et al. (1995) J. Lab. Clin. Med. 125:276-287.

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