Biocidal proteins

Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or... – The polynucleotide alters fat – fatty oil – ester-type wax – or...

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435 691, 435 701, 435 711, 435 713, 4351723, 4352404, 4352523, 4353201, 536 236, A01H 500, C12N 1529, C12N 504, C12N 1582

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active

056890486

ABSTRACT:
Biocidal proteins isolated from Mirabilis have been characterised. The proteins show a wide range of antifungal activity and are active against gram-positive bacteria. DNA encoding the proteins has been isolated and incorporated into vectors. Plants transformed with this DNA have been produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease-resistance.

REFERENCES:
patent: 4701522 (1987-10-01), Susumu
patent: 5340732 (1994-08-01), Habuka
patent: 5482928 (1996-01-01), De Bolle et al.
Cammue, et al. "Isolation and characterization of novel class of plant . . . , Journal of Biological Chemistry", vol. 267, No. 4, Feb. 1992, pp. 2228-2233.
Hubuka, et al. "Expression and secretion of Mirabilis antiviral protein in Escherichia . . . , "Journal of Biological Chemistry, vol. 262, No. 19, Jul. 1990, pp. 10988-10992.
Watson, et al. "Molecular Biology of the Gene, " The Benjamin/Cummings Publishing Company Inc., Menlo Park, CA, p. 313.

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