Biocidal proteins

Multicellular living organisms and unmodified parts thereof and – Plant – seedling – plant seed – or plant part – per se – Higher plant – seedling – plant seed – or plant part

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800279, 4352523, 536 236, A01H 500, C12N 1529, C12N 1570, C12N 1574, C12N 1582

Patent

active

059426632

ABSTRACT:
Biocidal proteins isolated from Mirabilis have been characterized. The proteins show a wide range of antifungal activity and are active against gram-positive bacteria. DNA encoding the proteins has been isolated and incorporated into vectors. Plants transformed with this DNA have been produced. The proteins find commercial application as antifungal or antibacterial agents; transformed plants will show increased disease-resistance.

REFERENCES:
patent: 4701522 (1987-10-01), Susumu
patent: 5340732 (1994-08-01), Habuka
patent: 5482928 (1996-01-01), DeBolle
Cammue et al., "Isolation and characterization of a novel class of plant . . . ", Journal of Biological Chemistry, vol. 267, No. 4, Feb. 1992, pp. 2228-2233.
Hubuka et al., "Expression and secretion of Mirabilis antiviral protein in Escherichia . . . ", Journal of Biological Chemistry, vol. 262, No. 19, Jul. 1990, pp. 10988-10992.
Watson et al., "Molecular Biology of the Gene", The Benjamin/Cummings Publishing Company Inc., Menlo Park, Ca, p. 313.

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