Biocidal isothiourea compounds

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424263, 424285, 2603472, 2604534, 546305, C07C12300, C07D21374, A01N 4340, A01N 4742

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active

042333180

ABSTRACT:
Novel biocidal S-aminoalkyl isothiourea compounds have the general structural formula ##STR1## wherein X is halogen; R is a straight or branched chain alkyl radical containing 5 to 20 carbon atoms; R.sub.1 is selected from the group consisting of alkyl containing 1 to 20 carbon atoms, alkenyl containing 2 to 6 carbon atoms, benzyl, halo substituted benzyl, .alpha.-methyl benzyl, furfuryl and pyridyl methyl; R.sub.2 is hydrogen or alkyl containing 1 to 10 carbon atoms; R.sub.3 and R.sub.4 are independently hydrogen or alkyl containing 1 to 4 carbon atoms; and R.sub.5 is divalent alkylene containing 2 to 4 carbon atoms.

REFERENCES:
patent: 3371010 (1968-02-01), Hamilton et al.
patent: 3513197 (1970-05-01), Daum et al.
Hino et al., Chemical and Pharmaceutical Bulletin, vol. 14, No. 11, Nov. 1966 (Japan).
Westland et al., Journal of Medicinal Chemistry, vol. 11, No. 1, Jan. 1968.

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