Biocidal gas sterilization and gas leakage determination

Chemical apparatus and process disinfecting – deodorizing – preser – Process disinfecting – preserving – deodorizing – or sterilizing – Step of warning or decreasing hazard of process

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422 3, 422 33, 422 34, 422117, A61L 220

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044578920

ABSTRACT:
Methods and apparatus for the timely determination of potentially harmful biocidal gas leakage from a pressurized chamber during sterilizing operations are disclosed. Biocidal gas make-up values are monitored during the sterilizing phase to provide prompt warning of biocidal gas leakage. In one embodiment, the timing of preselected pressure increment gas make-up charges are measured and compared to minimum acceptable gas make-up charge times. In addition, absorption of biocidal gas by the load can be compensated for in sterilizing operations where load absorption is a significant factor. Also, provision is made for predicting gas absorption by the load from steam absorption data obtained during pressure-controlled conditioning cycles.

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"Developments in Industrial Microbiology"; vol. 18,; Soc. for Industrial Microbiology; pp. 335-351.
J. J. Perkins; "Principles & Methods of Sterilization in Health Sciences"; Pbl. by C. C. Thomas; Springville, Ill, pp. 520-527.

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