Biocidal derivatives of catechins

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514333, 549400, 546257, A61K 3135, C07D31132

Patent

active

047600888

ABSTRACT:
Sulfide derivatives of catechins derived from condensed tannins have broad spectrum biocidal characteristics. Epicatechin-4-alkylsulfides and cupric complexes thereof containing up to 20, preferably 5 to 15, carbon atoms are particularly effective biocides against wood rotting fungi and gram-positive bacteria.
Such sulfides are prepared by reacting condensed tannin, either in the form of a purified tannin extract or comminuted plant tissue, with an appropriate thiol under mild acidic conditions.

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patent: 4248789 (1981-02-01), Okada
patent: 4460578 (1984-07-01), Cervelle et al.
Thompson et al., J.C.S., Perkin I, (11), 1387-99 (1972).

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