Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1988-09-12
1989-05-30
Robinson, Allen J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
162161, 210764, 514515, A01N 4748, A01N 5700
Patent
active
048351440
ABSTRACT:
A bactericidal composition and method for inhibiting and controlling the growth of the capsulated, faculative bacterium, Klebsiella pneumoniae, are disclosed. The composition comprises an amount, effective for the intended purpose, of methylene bis(thiocyanate) and a tetraalkyl phosphonium halide compound. The method comprises administering between about 0.1 to about 200 parts of this combined treatment (based on one million parts of the desired aqueous system) to the particular water containing system for which treatment is desired.
REFERENCES:
patent: 3426134 (1969-02-01), Shema et al.
patent: 3898343 (1975-08-01), Swered et al.
patent: 4725587 (1988-02-01), Whitekettle et al.
Kelly, M. T. and Matsen, J. M., "In Vitro Activity, Synergism, and Testing Parameters of Amikacin with Comparisons to Other Aminoglycoside Antibiotics", Antimicrobial Agents and Chemotherapy, 9:440-447 (1976).
Kull, F. C. et al., "Mixtures of Quaternary Ammonium Compounds and Long-Chain Fatty Acids as Antifungal Agents", Applied Microbiology, 9:538-541 (1961).
Research Disclosure #22520, p. 4, 1/10/83.
Donofrio Deborah K.
Whitekettle Wilson K.
Betz Laboratories Inc.
Ricci Alexander D.
Robinson Allen J.
Tobe Roslyn T.
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