Biochemical method for preparation of optically active carnitine

Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Resolution of optical isomers or purification of organic...

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435128, C07P 4100

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046364714

ABSTRACT:
L-carnitine is produced by bringing apocarnitine into contact with hydrase produced by a strain of Enterobacter in an aqueous medium having a pH of 4-10 at a temperature of 20.degree.-60.degree. C., whereby apocarnitine is converted to L-carnitine.

REFERENCES:
patent: 4371618 (1983-02-01), Cavazza
Fujita et al., (1961), Chemical and Pharmaceutical Bulletin, vol. 9, No. 9, pp. 661-665.
Dunn et al., (1981), The Journal of Biological Chemistry, vol. 256, No. 23, pp. 12437-12444.
Vandecosteele, (1980), Applied and Environmental Microbiology, vol. 39, No. 2, pp. 327-334.

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