Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2007-12-11
2007-12-11
Le, Long V. (Department: 1641)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C436S518000, C436S524000, C436S527000, C435S007100, C435S283100, C435S287100, C435S287200, C435S288700, C422S050000, C422S067000, C422S068100, C422S082050, C422S082090, C359S577000, C359S580000, C359S586000, C359S589000
Reexamination Certificate
active
11007366
ABSTRACT:
A simple and convenient sensor and measuring apparatus utilizing the optical interference effect of an optical thin film capable of measuring the binding between biochemical substances at a high throughput and having alkali resistance. An optical thin film of silicon nitride is disposed on the first surface and the rear surface of a silicon substrate, and the thickness of the silicon nitride film is modified in a direction parallel to the film. A portion of the thin film with increased thickness is used as a sensor upon which a probe is disposed, and over which a sample-containing solution is caused to flow. The binding between the probe and biochemical sample is detected based upon the change of the intensity of reflected light.
REFERENCES:
patent: 4558012 (1985-12-01), Nygren et al.
patent: 4820649 (1989-04-01), Kawaguchi et al.
patent: 4822566 (1989-04-01), Newman
patent: 5418136 (1995-05-01), Miller et al.
patent: 5468606 (1995-11-01), Bogart et al.
patent: 5482830 (1996-01-01), Bogart et al.
patent: 5494829 (1996-02-01), Sandstrom et al.
patent: 5541057 (1996-07-01), Bogart et al.
patent: 5550063 (1996-08-01), Bogart
patent: 5552272 (1996-09-01), Bogart
patent: 5629214 (1997-05-01), Crosby
patent: 5631171 (1997-05-01), Sandstrom et al.
patent: 5639671 (1997-06-01), Bogart et al.
patent: 5869272 (1999-02-01), Bogart et al.
patent: 6933112 (2005-08-01), Drewes et al.
patent: 2004/0070764 (2004-04-01), Fujimura
patent: 2007/0063304 (2007-03-01), Matsumoto et al.
patent: 2004-132799 (2002-10-01), None
patent: WO 94/03774 (1993-06-01), None
patent: WO 2004/031760 (2003-08-01), None
Jenison, R., et al., “Inteference-based detection of nucleic acid targets on optically coated silicon”, Nature Biotechnology Vo. 19, Jan. 2001, pp. 62-65.
Sandstrom, T., et al. “Visual detection of organic monomolecular films by interference colors”, Applied Optics, vol. 24, No. 4, Feb. 15, 1985, pp. 472-479.
Poenar, D.P., et al., “Colour sensors based on active inteference filters using silicon-compatible materials”, Elseiver, Sensors and Actuators, 1997, pp. 513-523.
Torbjörn Sandström et al., “Visual Detection of Organic Monomolecular Films by Inteference Colors”, Applied Optics, vol. 24, No. 4 (Feb. 15, 1985), pp. 472-479.
A. Brecht et al., “Optimised Layer Systems for Immunosensors Based on the RIFS Transducer”, Fresenius J. Anal. Chem (1994), pp. 360-366.
Dietmar Leipert et al., “Interaction Between Volatile Organic Compounds and Cyclopeptides Detected with Reflectometric Interference Spectroscopy”, Analytica Chimica Acta, vol. 392 (1999), pp. 213-221.
Fujimura Toru
Goto Yasushi
A. Marquez, Esq. Juan Carlos
Fisher Esq. Stanley P.
Hitachi , Ltd.
Le Long V.
Reed Smith LLP
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