Biocatalytic solgel microarrays

Details Biocatalytic solgel microarrays Biocatalytic solgel microarrays

2006-11-13

2010-12-07

Lam, Ann Y (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Reexamination Certificate

active

07846747

ABSTRACT:
A system and method for conducting high-throughput interactions between test compositions and analytes, comprising one or more test compositions, and a plurality of independent micromatrices, wherein each said micromatrix encapsulates at least one said test composition; and said micromatrices are made of a material that is permeable to an analyte.

REFERENCES:
patent: 3650900 (1972-03-01), Levin et al.
patent: 4307070 (1981-12-01), Oberhardt et al.
patent: 5200334 (1993-04-01), Dunn et al.
patent: 5474915 (1995-12-01), Dordick et al.
patent: 5512474 (1996-04-01), Clapper et al.
patent: 5552270 (1996-09-01), Khrapko et al.
patent: 5618933 (1997-04-01), Dordick et al.
patent: 5763430 (1998-06-01), Zasloff
patent: 5770721 (1998-06-01), Ershov et al.
patent: 5783431 (1998-07-01), Peterson et al.
patent: 5824526 (1998-10-01), Avnir et al.
patent: 5854030 (1998-12-01), Dordick et al.
patent: 6017760 (2000-01-01), Jauregui et al.
patent: 6051380 (2000-04-01), Sosnowski et al.
patent: 6153380 (2000-11-01), Nolan et al.
patent: 6171856 (2001-01-01), Thigpen et al.
patent: 6303290 (2001-10-01), Liu et al.
patent: 6573369 (2003-06-01), Henderson et al.
patent: 6660481 (2003-12-01), Rosenquist et al.
patent: 6780584 (2004-08-01), Edman et al.
patent: 2001/0055797 (2001-12-01), Conroy et al.
patent: 2002/0015952 (2002-02-01), Anderson et al.
patent: 2002/0020931 (2002-02-01), Stowell et al.
patent: 2002/0028506 (2002-03-01), Ho et al.
patent: 62-156651 (1987-07-01), None
patent: 11 337552 (1999-12-01), None
patent: 96/01836 (1996-01-01), None
patent: WO 00/54882 (2000-09-01), None
patent: WO 00/54882 (2000-09-01), None
patent: 01/021838 (2001-03-01), None
patent: WO 02/10761 (2002-02-01), None
Livage et al., “Encapsulation of biomolecules in silica gels”, Journal of Physics: Condensed Matter, vol. 13, pp. R673-R691, (2001).
Chauret N., et al., “Description of a 96-well plate assay to meausre cytochromes p4503A inhibition in human liver microsomes using a selective fluorescent probe,”Anal. Biochem., 276: 215-226 (1999).
Crespi, C.L., et al., “Microtiter plate assays for inhibition of human, drug-metabolism cytochromes P450,”Anal. Biochem., 248: 188-190 (1997).
Gill, I., et al., “Encapsulation of biologicals within silicate, siloxane, and hybrid sol-gel polymers: an efficient and generic approach,”J. Am. Chem. Soc., 120(34):8587-8598 (1998).
Gill, I., et al., “Bioencapsulation within synthetic polymers (Part I): sol-gel encapsulated biologicals,”TIBTECH, 18:282-296 (2000).
Iwatsubo, T., et al., “Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data,”Pharmacol. Ther., 73: 147-171 (1997).
Kim, Y., et al., “Stable sol-gel microstructured and microfluidic networks for protein patterning,”Biotechnology&Bioengineering, 73(5): 331-337 (2001).
Kim, J., et al., “Protease-containing silicates as active antifouling materials,”Biotechnology Prog., 18(3): 551-555 (2002).
Lake, B.G., et al., “Induction of CYP3A Isoforms in cultured precision-cut human liver slices,”Xenobiotica27: 1165-1173 (1997).
Nagy, G., et al., “Amperometric microcell for enzyme activity measurements,”Analytical Chemistry, 70(10):2156-2162 (1998).
Novick, S.J., et al., “Preparation of active and stable biocatalytic hydrogels for use in selective transformations,”Chemistry of Materials, 10(4): 955-958 (1998).
Novick, S.J., et al., “Investigating the effects of polymer chemistry on activity of biocatalytic plastic materials,”Biotechnology and Bioengineering, 68(6): 665-671 (2000).
Park, C.B., “Sol-gel encapsulated enzyme arrays for high-throughput screening of biocatalytic activty,”Biotechnology&Bioengineering, 78(2): 229-235 (2002).
Sergeeva, M.V., et al., “Peptide synthesis using proteases dissolved in organic solvents,”Enzyme Microbial Technogy, 20: 623-628 (1997).
Silber, P.M., et al., “In vitro methods for predicting human toxicity,”Lab Animal, 23: 33-37 (1994).
Wang, P., et al., “Biocatalytic plastics as active and stable materials for biotransformations,”Nature Biotechnology,15: 789-793 (1997).
Zomorodi, K. et al., “Kinetics of diazepam metabolism in rat hepatic microsomes and hepatocytes and their use in predicting in vivo hepatic clearance,”Xenobiotica, 25: 907-916 (1995).
Livage, et al., “Encapsulation of Biomolecules in Silica Gels,”J. Physics: Condensed Matter, 13: R673-R69 (2001).
Buters, et al., “cDNA-Directed Expression of Human Cytochrome p450 CYP1A1 Using Baculovirus,”Drug Metabolism and Disposition, 23(7): 696-701 (1995).

Affiliated with

Also associated with

Rating

Biocatalytic solgel microarrays does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biocatalytic solgel microarrays, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biocatalytic solgel microarrays will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4235539