Biocatalytic process for the production of L-(-)-carnitine from

Details Biocatalytic process for the production of L-(-)-carnitine from Biocatalytic process for the production of L-(-)-carnitine from

1993-01-07

1994-04-05

Knode, Marian

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing nitrogen-containing organic compound

4352521, 435280, 435873, C12P 1300, C12N 120

Patent

active

053004302

ABSTRACT:
A process is described for stereospecifically hydrating crotonobetaine to L-(-)-carnitine via the action of an enzyme produced by four new strains of Proteus mirabilis (NRRL B-18480, NRRL B-18481, NRRL B-18482, and NRRL B-18483) in biotransformation media containing from 10 to 12% (w/v) crotonobetaine inner salt.

REFERENCES:
patent: 4650759 (1987-03-01), Yokozeki et al.
patent: 4906568 (1990-03-01), Jung et al.
Sum et al., "Synthesis of L(-)-carnitine by Hydration of Crotonobetaine by Interobacteria," Appl. Microbiol. Biotechnol.:27 pp. 538-544, 1988.

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