Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing
Patent
1994-05-17
1998-12-15
Hollinden, Gary E.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
119 65, 119 66, 119654, 119653, 119863, 119865, 119864, 43107, 43121, A61K 4900, A01K 2900, A62B 3500, A01M 120
Patent
active
058492623
ABSTRACT:
The present invention is directed to a bioassay system for retaining hematophagous arthropods, such as, but not limited to, fleas, ticks and flies, in a microenvironment which mimics the natural conditions of unconfined hematophagous arthropods feeding on an animal. The bioassay system of the present invention comprises a container and an attachment means capable of maintaining hematophagous arthropods under conditions such that the fecundity of the retained hematophagous arthropods is substantially equivalent to the fecundity of unconfined hematophagous arthropods. The container is attached to an animal by an attachment means capable of immobilizing the container to the animal in such a manner that hematophagous arthropods can feed undisturbed from the animal through the container. In one embodiment, hematophagous arthropods are retained in a container comprising a retaining means penetrable by the mouth parts of hematophagous arthropods and a gas exchange means. The present invention also relates to the use of the bioassay system to identify agents capable of inhibiting hematophagous arthropod infestation. The bioassay system of the present invention can be part of a kit used to identify anti-hematophagous arthropod infestation agents.
REFERENCES:
patent: 4850305 (1989-07-01), Georgi et al.
patent: 4900876 (1990-02-01), Bushman et al.
patent: 4967698 (1990-11-01), Kennedy
patent: 5133289 (1992-07-01), Georgi
patent: 5381557 (1995-01-01), Luria et al.
Dryden, Dissertation, pp. 68-71, in "Blood Consumption and Feeding Behavior of the Cat Flea, Ctenocephalides felis felis (Bouche 1835)", Purdue University, May, 1990.
Dryden, pp. 23-27, 1989, Companion Animal Practice, vol. 19, No. 3.
Dryden, pp. 117-122, 1989, Vet. Parasit., vol. 34.
Hink et al., pp. 424-427, 1991, J. Med. Entomol., vol. 28, No. 3.
Hudson et al., pp. 1126-1129, 1958, Bull. Wld. Hlth. Org., vol. 19.
Jellison et al., pp. 1081-1082, 1933, Pub. Health Rep., vol. 48, No. 35.
Kern et al., pp. 203-206, 1992, J. Med. Entomol., vol. 29, No. 2.
Osbrink et al., pp. 727-731, 1984, J. Med. Entomol., vol. 21, No. 6.
Silverman et al., pp. 78-83, 1981, J. Med. Entomol., vol. 18, No. 1.
Popiel Irene
Thomas Rex E.
Wallenfels Lynda
Hartley Michael G.
Heska Corporation
Hollinden Gary E.
LandOfFree
Bioassay system for arthropods which elastically attaches to an does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Bioassay system for arthropods which elastically attaches to an , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bioassay system for arthropods which elastically attaches to an will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1454967