Bioadhesive tablet for non-systemic use products

Details Bioadhesive tablet for non-systemic use products Bioadhesive tablet for non-systemic use products

1993-01-29

1994-07-19

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424440, 424464, 424465, 424468, 424470, 424488, A61K 914, A61K 920, A61K 950, A61K 968

Patent

active

053307615

ABSTRACT:
The present invention relates to a controlled release bioadhesive tablet which includes a locally active agent, a heterodisperse gum matrix, and a pharmaceutically acceptable diluent. In certain preferred embodiments, the tablet further includes an additional bioadhesive agent. The final product adheres to mucous membranes and releases the locally active agent over a desired period of time. Also disclosed is a bioadhesive excipient useful in the preparation of these tablets.

REFERENCES:
patent: 4740365 (1988-04-01), Yukimatsu et al.
patent: 4829056 (1989-05-01), Sugden
patent: 4915948 (1990-04-01), Gallopo et al.
patent: 4994276 (1991-02-01), Baichwal et al.
patent: 5077051 (1991-12-01), Gallopo et al.
patent: 5128143 (1992-07-01), Baichwal et al.
patent: 5135757 (1992-08-01), Baichwal et al.
patent: 5169639 (1992-12-01), Baichwal et al.

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