Bioadhesive pharmaceutical carrier

Details Bioadhesive pharmaceutical carrier Bioadhesive pharmaceutical carrier

1991-09-25

1993-03-09

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514536, 514779, 514781, 514902, 514944, 514966, 514967, 514969, 424426, 424433, 424434, 424435, 424436, 424488, 424 60, 424DIG14, 424DIG15, 106 35, 433215, 4332171, 433226, 4332281, 523115, 523116, 523118, 523120, A61K 902, A61K 906, A61K 4700, A61L 1503

Patent

active

051928027

ABSTRACT:
Bioadhesive pharmaceutical carrier consisting essentially of a polymer blend of sodium carboxymethyl cellulose and xanthan gum or sodium alginate. The invention also provides for a method of control releasing a pharmaceutical active comprising incorporating an active into the bioadhesive pharmaceutical carrier. The invention is particularly adaptable for oral use and teething gels.

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Gurney et al. Biomaterials 5(6): 336-340 (1984) Bioadhesive Intraoral Release Systems.
Groselj et al. Zoboz drav. vestn. 36(314): 71-5 (1981) Clinical Comparison of Adhesiveness: Adhesive Vehicles, Orabase, on Oral Mucous Membranes.
Mofenson et al. Clin. Pediatr. 22(3): 190-192 (1983) Lidocaine (2% Viscous)(for Teething) Toxicity from Topical Mucosal Application.

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