Bioactive oligopeptides

Details Bioactive oligopeptides Bioactive oligopeptides

2006-09-05

2006-09-05

Chism, B. Dell (Department: 1654)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C514S002600, C514S017400, C514S018700

Reexamination Certificate

active

07101664

ABSTRACT:
The invention relates to short 3- to 10-mer bioactive oligopeptides composed of amino acid residues selected from the group consisting of glycine, alanine, β-alanine, serine, histidine, glutamic acid, aspartic acid, lysine and arginine. They are able to improve at least one cell culture parameter such as growth rate, viable cell number, viability on day 6 or 7, or final product yield, when added to the basal nutrient medium. The invention further relates to mixtures of such oligopeptides and to a method of improving cell culture parameters by incubating animal or plant cells in the presence of said oligopeptides.

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Database Medline (Online), US National Library of Medicine (NLM), XP002172992 & In Vitro, vol. 17, No. 6, pp. 459-466 (1981).

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