Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Processes of preparing a desired or intentional composition...
Reexamination Certificate
2007-06-12
2007-06-12
Cain, Edward J. (Department: 1714)
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
Processes of preparing a desired or intentional composition...
C523S114000, C523S115000
Reexamination Certificate
active
10630092
ABSTRACT:
Orthopedic compositions are provided that include a homogeneous mixture of a biocompatible polymer and a bioactive particulate ceramic wherein the ceramic has an average particle size of not more than 500 nm are provided. The compositions may be used to form bone cement or various spinal implants, including spinal spacers, interbody fusion cages, bone plates and bone screws. Methods for stabilizing a spine, for correcting a bone defect, and for promoting fusion of adjacent vertebrae are also provided.
REFERENCES:
patent: 4131597 (1978-12-01), Bluethgen et al.
patent: 4192021 (1980-03-01), Deibig et al.
patent: 4437836 (1984-03-01), Schmitz-Josten et al.
patent: 4516276 (1985-05-01), Mittelmeier et al.
patent: 4623553 (1986-11-01), Ries et al.
patent: 4636526 (1987-01-01), Dorman et al.
patent: 4743229 (1988-05-01), Chu
patent: 4776890 (1988-10-01), Chu
patent: 4888366 (1989-12-01), Chu et al.
patent: 5001169 (1991-03-01), Nathan et al.
patent: 5002582 (1991-03-01), Guire et al.
patent: 5015247 (1991-05-01), Michelson
patent: 5035715 (1991-07-01), Smestad et al.
patent: 5091344 (1992-02-01), Enomoto et al.
patent: 5123925 (1992-06-01), Smestad et al.
patent: 5204319 (1993-04-01), Enomoto et al.
patent: 5217492 (1993-06-01), Guire et al.
patent: 5246457 (1993-09-01), Piez et al.
patent: 5273964 (1993-12-01), Lemons
patent: 5320844 (1994-06-01), Liu
patent: 5338772 (1994-08-01), Bauer et al.
patent: 5364399 (1994-11-01), Lowery et al.
patent: 5380298 (1995-01-01), Zabetakis
patent: 5468544 (1995-11-01), Marcolongo et al.
patent: 5480438 (1996-01-01), Arima et al.
patent: 5645934 (1997-07-01), Marcolongo et al.
patent: 5669909 (1997-09-01), Zdeblick et al.
patent: 5679723 (1997-10-01), Cooper et al.
patent: 5721049 (1998-02-01), Marcolongo et al.
patent: 5728753 (1998-03-01), Bonfield et al.
patent: 5776193 (1998-07-01), Kwan et al.
patent: 5782919 (1998-07-01), Zdeblick et al.
patent: 5817328 (1998-10-01), Gresser et al.
patent: 5858318 (1999-01-01), Luo
patent: 5914356 (1999-06-01), Erbe
patent: 5964807 (1999-10-01), Gan et al.
patent: 5972368 (1999-10-01), McKay
patent: 5977204 (1999-11-01), Boyan et al.
patent: 6027742 (2000-02-01), Lee et al.
patent: 6033438 (2000-03-01), Bianchi et al.
patent: 6139585 (2000-10-01), Li
patent: 6152927 (2000-11-01), Farris et al.
patent: 6165486 (2000-12-01), Marra et al.
patent: 6270347 (2001-08-01), Webster et al.
patent: 0 747 067 (1996-12-01), None
patent: WO 00/57932 (2000-10-01), None
patent: WO 01/01930 (2001-01-01), None
patent: WO 01/54746 (2001-08-01), None
patent: WO 02/22117 (2002-03-01), None
Allograft Catalog, University of Florida Tissue Bank, Inc., LIT.UF.CT96 Rev. A/98.
Tangent Cortical Wedge Mechanical Testing, Regeneration Technologies, Inc., ©1999 RTI.
Flahiff, C.M. et al., “Analysis of a biodegradable composite for bone healing”,Journal of Biomedical Materials Research, 32:419-424 (1996).
Verheyen, C.C.P.M. et al., “Hydroxylapatite/poly(L-lactide) composites: An animal study on push-out strengths and interface histology”,Journal of Biomedical Materials Research, 27:433-444 (1993).
Verheyen, C.C.P.M. et al., “Evaluation of hydroxylapatite/poly(L-lactide) composites: Mechanical behavior”,Journal of Biomedical Materials Research, 26:1277-1296 (1992).
Furukawa, T. et al., “Histomorphometric study on high-strength hydroxyapatite/poly(L-lactide) composite rods for internal fixation of bone fractures”,Journal of Biomedical Materials Research, 50:410-419 (2000).
Yasunaga, T. et al., “Bonding behavior of ultrahigh strength unsintered hydroxyapatite particles/poly(L-lactide) composites to surface of tibial cortex in rabbits”,Journal of Biomedical Materials Research, 47:412-419 (2000).
Watanabe, S. et al., “Traumatic Sternal Segment Dislocation in a Child”,CHEST, 96(3):684-686 (1989).
Shikinami, Y. et al., “Bioresorbable devices made of forged composites of hydroxyapatite (HA) particles and poly-L-lactide (PLLA): Part I. Basic characteristics”,Biomaterials, 20:859-877 (1999).
Doyle, C. et al.,“In vitroandin vivoevaluation of polyhydroxybutyrate and of polyhydroxybutyrate reinforced with hydroxyapatite”,Biomaterials, 12:841-847 (1991).
Higashi, S. et al., “Polymer-hydroxyapatite composites for biodegradable bone fillers”,Biomaterials, 7:183-187 (1986).
Bonfield, W. et al., “Hydroxyapatite reinforced polyethylene—a mechanically compatible implant material for bone replacement”,Biomaterials, 2:185-186 (1981).
Hamadouche, M. et al., “TheIn vivoBioactivity of Sol-Gel Bioactive Glasses Coated Alumina Implants”, 46thAnnual Meeting, Orthopaedic Research Society, 0174 (2000).
Orefice, R.L. et al., “Processing and Characterization of Bioactive Polysulfone-Bioglass® Composites”,Bioceramics, 8:409-414, Eds. Wilson, J. et al., Florida, USA, Perganon (1995).
Liu, Qing et al.: “Nano-apatite/polymer composites: mechanical and physicochemical characteristics”. BIOMATERIALS, 1997 Elsevier Science Limited, GB. ISSN: 0142-9612.
Chaffin Kimberly A.
Trieu Hai H.
Cain Edward J.
SDGI Holdings Inc.
Woodard Emhardt Moriarty McNett & Henry LLP
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