Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1989-01-11
1991-08-13
Draper, Garnette D.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
530345, 530351, 530405, 530409, 514 2, 514 12, 424 851, 424 852, C07K 700, A61K 3702
Patent
active
050397907
ABSTRACT:
The present invention discloses a peptide capable of blocking activity of Interleukin-1. The peptide corresponds to the 157-186 amino acid residue of the IL-1.beta. molecules.
REFERENCES:
patent: 4762914 (1988-08-01), Auron et al.
patent: 4766069 (1988-08-01), Auron et al.
patent: 4772685 (1988-09-01), Schmidt
patent: 4774320 (1988-09-01), Tagliabue et al.
patent: 4935343 (1990-06-01), Allison et al.
patent: 4994553 (1991-02-01), Schmidt
Boraschi et al, Biotherapy, 1989, pp. 377-389.
Huang et al, Mol. Biol. Med. 4(3), 1987, pp. 169-181.
Kamagashira et al, J. Biochem 1988, 104(5) pp. 837-840.
March et al, Nature 315, 1985, pp. 641-647.
Mosley et al, PNAS 84, 1987, pp. 4572-4576.
Yem et al, Lymphokine Res. vol. 7(2) 1988, pp. 85-92.
Dinarello et al. J. Immunol. 133(3) 1984, p. 1332-1338.
Rimsky et al, J. Immunol. 136(9) 1986, pp. 3304-3310.
Lillquist et al, J. Immunol. 141(6) 1988, pp. 1975-1981.
Antoni, G. et al. J. of Immunol. 137:3201(1986).
Ferreira, S. H. et al. Nature 334:698 (1988).
Rosenwasser L. J. et al, Proc. Natl. Acad. Sci. USA 83:5243 (1986).
Boraschi, D. et al. J. Exp. Med. 168:675 (1988).
Palaszynski, E. W., Biochem. and Biophys. Res. Comm. 147:204 (1987).
Auron, P. E., et al, J. Mol. Cell. Immunol. 2:169 (1985).
Adams Steven P.
Bulock Joseph W.
Fok Kam F.
Draper Garnette D.
Monsanto Company
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