Bioactive and/or targeted dendrimer conjugates

Details Bioactive and/or targeted dendrimer conjugates Bioactive and/or targeted dendrimer conjugates

1995-03-07

1998-02-03

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424 129, 424 133, 424 137, 424 141, 424 149, 424 93, 424 9322, 424 932, 424 936, 424 94, 424 942, 424 96, 424 7808, 424 931, 4241781, 4241931, 4242041, 4242341, 424280, 424DIG16, 424405, 424417, 514772, 523105, 525417, 935 52, 935 54, A61K 3174, A61K 914, A61K 31785

Patent

active

057141665

ABSTRACT:
Dendritic polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried material, where the carrier material can be a biological response modifier, have been prepared. The conjugate can also have a target director present, and when it is present then the carried material may be a bioactive agent. Preferred dendritic polymers are dense star polymers, which have been complexed with biological response modifiers. These conjugates and complexes have particularly advantageous properties due to their unique characteristics.

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